Biomedical Nano-Engineering Laboratory

The Wilhelm Lab is affiliated with the Stephenson School of Biomedical Engineering (SBME) at the University of Oklahoma (OU).

OU stephenson-biomedical-engineering




Our lab space is in Gallogly Hall at the OU Norman Campus.

Our research interests include the engineering and designing of nanomaterials for use in biomedical applications and clinical translation.



Publication in Advanced Materials

May 2024 – Dr. Lin Wang and the team published an original research paper in the journal Advanced Materials! Thank you to our collaborators and congratulations!

L. Wang, V. Sheth, K. Liu, P. Panja, A. N. Frickenstein, Y. He, W. Yang, A. G. Thomas, M. H. Jamei, J. Park, S. Lyu, N. D. Donahue, W. R. Chen, R. Bhattacharya, P. Mukherjee, S. Wilhelm, “Primary Human Breast Cancer-Associated Endothelial Cells Favor Interactions with Nanomedicines”
Advanced Materials, 2024, published online.
DOI: 10.1002/adma.202403986  | PDF (7.0 MB)

BE4NANO hosts OUHSC College of Medicine Club Scrubs Students

April 2024 – The Wilhelm Lab BE4NANO program hosted high school students from the OUHSC College of Medicine Club Scrubs initiative. Club Scrubs is a hands-on, exciting, interactive club for high school students interested in exploring health and STEM careers.

2024 Student Awards

April 2024 – Congratulations to our Wilhelm Lab undergraduate students, Thao and Hamilton!

Thao: President’s Outstanding Sophomore Award

Hamilton: Gallogly College of Engineering Outstanding Senior in BME Award

BE4NANO Outreach at “Kids Night with Microscopes” Event

April 2024 – The Wilhelm Lab team participated recently in the “Kids Night with Microscopes” outreach event organized by the Oklahoma Microscopy Society and the OU SRNML. Thank you for the invitation and the opportunity to share our bionanotechonlogy research.

Presidential Professorship and Endowed Chair

April 2024 – Dr. Stefan Wilhelm received the William H. Barkow Presidential Professorship and the Stephenson Endowed Chair #5 in Biomedical Engineering.


April 2024 – Wilhelm Lab undergraduate student Hamilton Young received the NSF GRFP award! Outstanding accomplishment, Hamilton!

2024 SBME Awards and Dr. Lin Wang’s Farewell

March 2024 – An eventful day for the Wilhelm Lab with the following SBME awards presented to:

  • Vinit, Outstanding PhD Graduate
  • Hamilton, Outstanding Senior
  • Thao, Outstanding Sophomore

And a postdoc farewell for Dr. Lin Wang. Thank you!

BE4NANO Day @OUHSC – March 2024

March 2024 – Our BE4NANO students from the Caddo-Kiowa Technology Center visited the OUHSC College of Nursing to learn about healthcare skills. Thanks the College of Nursing team for the support!

BE4NANO Day – March 2024

March 2024 – We hosted high school students from the Caddo-Kiowa Technology Center for our BE4NANO Day. Thanks to the SBME and GCoE teams for the support!

Publication in Nano Letters

January 2024 – Hamilton Young, Yuxin He, and the team published a review article in the journal Nano Letters.

H. Young, Y. He, B. Joo, S. Ferguson, A. Demko, S. K. Butterfield, J. Lowe, N. F. Mjema, V. Sheth, L. Whitehead, M. J. Ruiz-Echevarria, S. Wilhelm, “Toward the scalable, rapid, reproducible, and cost-effective synthesis of personalized nanomedicines at the point of care”
Nano Letters, 2024, published online.
DOI: 10.1021/acs.nanolett.3c04171 | PDF (4.0 MB)

Publication in Advanced Functional Materials

November 2023 – Dr. Lin Wang and the team published a review article in the journal Advanced Functional Materials.

L. Wang, S. Quine, A. N. Frickenstein, M. Lee, W. Yang, V. M. Sheth, M. D. Bourlon, Y. He, S. Lyu, L. Garcia-Contreras, Y. D. Zhao, S. Wilhelm, “Exploring and analyzing the systemic delivery barriers for nanoparticles”
Advanced Functional Materials, 2023, published online.
DOI: 10.1002/adfm.202308446 | PDF (5.5 MB)

Ph.D. Defense – Vinit Sheth

November 2023 – Vinit Sheth defended his Ph.D. thesis “Establishing three-dimensional super-resolution microscopy methods for quantifying intracellular nanoparticle distribution”. Congratulations, Dr. Sheth! Thank you to the Ph.D. committee members, Drs. Wei Chen, Qinggong Tang, and JP Masly.

Caddo-Kiowa Technology Center STEM Day – Fall 2023

November 2023 – We participated in the Caddo-Kiowa Technology Center STEM Day together with 150 high school students. Thanks to the various OU and OUHSC colleagues for the support!

Fall 2023 – BE4NANO Classroom Visit

November 2023 – Our SBME faculty team visited the pre-engineering and biomedical sciences high school classrooms at the Caddo-Kiowa Technology Center in Fort Cobb to engage students in bionanotechnology, bioimaging, and biomedical engineering.

Wilhelm Lab Team – Fall 2023

October 2023 – Group picture of the Wilhelm Lab team members.

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