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WILHELM LAB

Biomedical Nano-Engineering Laboratory

OU stephenson-biomedical-engineeringThe Wilhelm Lab is affiliated with the Stephenson School of Biomedical Engineering (SBME) at the University of Oklahoma (OU).

Our lab space is in Gallogly Hall at the OU Norman Campus.

Our research interests include engineering and design of nanomaterials for use in biomedical applications and clinical translation.


WILHELM LAB NEWS

Publication in Annual Review of Pharmacology and Toxicology

January 2021 – Wen Yang, Lin Wang, and Evan Mettenbrink published a review article in the journal Annual Review of Pharmacology and Toxicology in collaboration with Prof. Paul DeAngelis (OUHSC).

W. Yang, L. Wang, E. Mettenbrink, P. L. DeAngelis, S. Wilhelm, “Nanoparticle toxicology.“
Annual Review of Pharmacology and Toxicology, 2021, 61, 269-289.

DOI: 10.1146/annurev-pharmtox-032320-110338 | PDF (1.9 MB)

BE4NANO – Virtual Classroom Visit – Caddo-Kiowa Technology Center in Fort Cobb

December 2020 – As part of the “Bionanotechnology Engagement for Native Americans in Oklahoma” (BE4NANO) outreach and education initiative, Wilhelm Lab visited the Caddo-Kiowa Technology Center in Fort Cobb virtually via Zoom due to COVID19 restrictions to engage high school juniors in classroom hands-on demonstrations around bionanotechnology.

YouTube video from the Caddo-Kiowa Technology Center highlighting the BE4NANO outreach event:

Faculty Investment Program Award 2020

December 2020 – Wilhelm Lab received the Faculty Investment Program Award 2020 from the OU Vice President of Research and Partnerships.

Invited Presentations

November 2020 – Stefan Wilhelm delivered invited virtual talks at the University of Tennessee, Knoxville, Department of Chemical and Biomolecular Engineering, and the University of Minnesota, Minnesota Nano Center, Nanomedicine Workshop. Thank you for the invitations!

Publication in Advanced Functional Materials

November 2020 – Vinit Sheth and Lin Wang published an article in the journal Advanced Functional Materials in collaboration with Drs. Priyabrata Mukherjee and Resham Bhattacharya.

V. Sheth, L. Wang, R. Bhattacharya, P. Mukherjee, S. Wilhelm, “Strategies for delivering nanoparticles across tumor blood vessels.”
Advanced Functional Materials, 2020, published online.

DOI: 10.1002/adfm.20200736PDF (2.7 MB)

Publication in Bioactive Materials

September 2020 – Emmy Francek and Stefan Wilhelm co-authored a research article in the journal Bioactive Materials.

Y. Zhang, C.K. Elechalawar, M.N. Hossen, E.R. Francek, A. Dey, S. Wilhelm, R. Bhattacharya, P. Mukherjee, “Gold nanoparticles inhibit activation of cancer-associated fibroblasts by disrupting communication from tumor and microenvironmental cells.”
Bioactive Materials, 2021, 6, 326-332.

DOI:10.1016/j.bioactmat.2020.08.009  | PDF (0.6 MB)

OCAST Health Research Award 2020

August 2020 – Wilhelm Lab received the OCAST Health Research Award 2020.

Analytical and Bioanalytical Chemistry Cover – September 2020 Issue

August 2020 – “Assessing nanoparticle colloidal stability with Single-Particle Inductively Coupled Plasma Mass Spectrometry (SP-ICP-MS)” by Donahue et al. is highlighted on the September 2020 journal cover of Analytical and Bioanalytical Chemistry.

N. D. Donahue, E. R. Francek, E. Kiyotake, E. E. Thomas, W. Yang, L. Wang, M. S. Detamore, S. Wilhelm, “Assessing nanoparticle colloidal stability with Single-Particle Inductively Coupled Plasma Mass Spectrometry (SP-ICP-MS)”
Analytical and Bioanalytical Chemistry, 2020, 412, 5205-5216.

DOI: 10.1007/s00216-020-02783-6 | PDF (2.1 MB)

Outstanding Sophomore Award to Emmy Francek

July 2020 – Emmy Francek received the SBME Oustanding Sophomore Award 2020.

Publication in Science Advances

July 2020 – Stefan Wilhelm co-authored a research article in the journal Science Advances.

N. Hossen, L. Wang, H. R. Chinthalapally, J. D. Robertson, K. M. Fung, S. Wilhelm, M. Bieniasz, R. Bhattacharya, P. Mukherjee, “Switching intracellular pathway and enhancing therapeutic efficacy of small interfering RNA by auroliposome.”
Science Advances, 2020, 6, 30, eaba5379.

DOI: 10.1126/sciadv.aba5379PDF (2.3 MB)

Publication in Analytical and Bioanalytical Chemistry

July 2020 – Nathan Donahue, Emmy Francek, Emi Kiyotake, Emily Thomas, Wen Yang, and Lin Wang published a research article in the journal Analytical and Bioanalytical Chemistry.

N. D. Donahue, E. R. Francek, E. Kiyotake, E. E. Thomas, W. Yang, L. Wang, M. S. Detamore, S. Wilhelm, “Assessing nanoparticle colloidal stability with Single-Particle Inductively Coupled Plasma Mass Spectrometry (SP-ICP-MS).”
Analytical and Bioanalytical Chemistry, 2020, accepted.

DOI: 10.1007/s00216-020-02783-6PDF (2.1 MB)

Nature Materials Cover – May 2020 Issue

May 2020 – “The entry of nanoparticles into solid tumours” by Sindhwani et al. is highlighted on the May 2020 journal cover of Nature Materials.

S. Sindhwani, A.M. Syed, J. Ngai, B.R. Kingston, L. Maiorino, J. Rothschild, P. MacMillan, Y. Zhang, N.U. Rajesh, T. Hoang, J.L.Y. Wu, S. Wilhelm, A. Zilman, S. Gadde, A. Sulaiman, B. Ouyang, Z. Lin, L. Wang, M. Egeblad, W.C.W. Chan, “The entry of nanoparticles into solid tumours”
Nature Materials, 2020, 19, 566-575.

DOI: 10.1038/s41563-019-0566-2PDF (7.2 MB)