October 2022 – Tekena, a current BME junior in the Wilhelm Lab, received the Gallogly College of Engineering Pursuit of Excellence Award. Congratulations Tekena!

September 2022 – Vinit is a co-author of a collaborative research project led by Prof. Mukherjee (OUHSC). The paper has been published in  Advanced Science.

GOLD NANOPARTICLES DISRUPT THE IGFBP2/MTOR/PTEN AXIS TO INHIBIT OVARIAN CANCER GROWTH
M.N. Hossen, L.Wang, S.K.D. Dwivedi, Y. Zhang, G. Rao, C.K. Elechalwar, V. Sheth, A. Dey, S. Asfa, S.K. Gulla, C. Xu, K. Fung, J.D. Robertson, M. Bieniasz, S. Wilhelm, R. Bhattacharya, P. Mukherjee, “Gold nanoparticles disrupt the IGFBP2/mTOR/PTEN axis to inhibit ovarian cancer growth”
Advanced Science, 2022, published.
DOI: 10.1002/advs.202200491  | PDF (11.1 MB)

September 2022 – Evan Mettenbrink and Wen Yang published a review paper in Advanced Photonics Research.

BIOIMAGING WITH UPCONVERSION NANOPARTICLES
E. Mettenbrink, W. Yang, S. Wilhelm, “Bioimaging with upconversion nanoparticles”
Advanced Photonics Research, 2022, published.
DOI: 10.1002/adpr.202200098  | PDF (2.2 MB)

September 2022 – Wen Yang and her team published a paper in Nano Letters in collaboration with colleagues from OUHSC.

CONTROLLING NANOPARTICLE UPTAKE IN INNATE IMMUNE CELLS WITH HEPAROSAN POLYSACCHARIDES
W. Yang, A. N. Frickenstein, A. M. Holden, V. Sheth, E. M. Mettenbrink, L. Wang, A. Woodward, B. Joo, S. Butterfield, N. D. Donahue, D. E. Green, A. Thomas, T. Harcourt, Y. Hamilton, M. Tang, Z. Malik, R. Harrison, P. Mukherjee, P. L. DeAngelis, S. Wilhelm, “Controlling nanoparticle uptake in innate immune cells with heparosan polysaccharides.”
Nano Letters, 2022, published.
DOI: 10.1021/acs.nanolett.2c02226  | PDF (6.5 MB)

August 2022 – Stefan Wilhelm has been named the Faculty Fellow of the University of Oklahoma Vice President for Research and Partnership (OVPRP) office.

July 2022 – Wilhelm Lab received funding support for a Team Grant from the Presbyterian Health Foundation.

July 2022 – Wen Yang defended her Ph.D. thesis with the title “A novel polysaccharide-based surface engineering strategy for nanomedicines”. Congratulations, Dr. Yang! Thank you to the Ph.D. committee members, Drs. Handan Acar, Qinggong Tang, and Zhibo Yang.

July 2022 – The Wilhelm Lab team members in Summer 2022. An amazing group of young scientists and engineers.

PC: Travis Caperton.

May 2022 – High school students from the Caddo-Kiowa Technology Center in Fort Cobb participated in a week-long summer research camp.

May 2022 – Dr. Nathan Donahue and his team published a paper in Nano Letters in collaboration with colleagues from PerkinElmer.

ABSOLUTE QUANTIFICATION OF NANOPARTICLE INTERACTIONS WITH INDIVIDUAL HUMAN B CELLS BY SINGLE CELL MASS SPECTROMETRY
N. D. Donahue, V. Sheth, A. N. Frickenstein, A. Holden, S. Kanapilly, S. Chady, S. Wilhelm, “Absolute quantification of nanoparticle interactions with individual human b cells by single cell mass spectrometry”
Nano Letters, 2022, published online
DOI: 10.1021/acs.nanolett.2c01037 | PDF (2.5 MB)

April 2022 – High school students from the Caddo-Kiowa Technology Center in Fort Cobb visited the OU Gallogly College of Engineering and the OU Samuel Roberts Nobel Microscopy Laboratory as part of the 3rd BE4NANO DAY. Thank you to everyone involved for making this day a success, in particular Benjamin “BJ” Lee, the OU AISES student chapter, the GCoE Diversity, Equity, and Inclusion program (Lisa Morales), and the SRNML team (Andy Madden, Preston Larson, Julian Sabisch, and Tingting Gu).

April 2022 – Congratulations to our students who received the following awards:

• Nathan Donahue: Outstanding PhD Graduate Student (OU SBME)
• Evan Mettenbrink: Outstanding MS Graduate Student (OU SBME)
• Emmy Francek: Outstanding Senior (OU SBME); Letzeiser Award (OU); Campus Life Award (OU); Outstanding Senior (GCoE)
• Hamilton Young: Exemplary Sophomore (OU SBME)
• Wen Yang: Best Research Paper (OU SBME)
• Alex Frickenstein: Outstanding Teaching Assistant (OU SBME); SRNML Voucher Program Award (OU)
• Alyssa Holden: NSF GRFP Award
• Rylee Newport: Delta Gamma Scholarship (OU)

April 2022 – Wen Yang published a co-first author paper in the journal Biosensors with colleagues from OU, Iowa State University, and Tufts University. The project was led by Drs. Binbin Weng and Qing He.

LABEL-FREE DIFFERENTIATION OF CANCER AND NON-CANCER CELLS BASED ON MACHINE-LEARNING-ALGORITHM-ASSISTED FAST RAMAN IMAGING
Q. He*, W. Yang*, W. Luo, S. Wilhelm, B. Weng, “Label-free differentiation of cancer and non-cancer cells based on machine-learning-algorithm-assisted fast raman imaging”
Biosensors, 2022, 12, 250.

DOI: 10.3390/bios12040250 | PDF (2.3 MB)

April 2022 – We published a co-author paper in the International Journal of Molecular Sciences (IJMS) with colleagues from OUHSC. The project was led by Prof. James Battiste (Department of Neurosurgery and Stephenson Cancer Center, OUHSC).

PHYSICAL FORCES IN GLIOBLASTOMA MIGRATION: A SYSTEMATIC REVIEW
A. Grossen, K. Smith, N. Coulibaly, B. Arbuckle, A. Evans, S. Wilhelm, K. Jones, I. Dunn, R. Towner, D. Wu, Y.-T. Kim,  J. Battiste, “Physical forces in glioblastoma migration: a systematic review”
International Journal of Molecular Sciences, 2022, 23, 7, 4055.

DOI: 10.3390/ijms23074055 | PDF (1.3 MB)

April 2022 – Wilhelm Lab undergraduate student Alyssa Holden received the NSF GRFP award! Outstanding accomplishment, Alyssa!