WILHELM LAB
Biomedical Nano-Engineering Laboratory
The Wilhelm Lab is affiliated with the Stephenson School of Biomedical Engineering (SBME) at the University of Oklahoma (OU).
Our lab space is in Gallogly Hall at the OU Norman Campus.
Our research interests include engineering and design of nanomaterials for use in biomedical applications and clinical translation.
WILHELM LAB NEWS
Caddo-Kiowa Technology Center – STEM Day
March 2023 – We participated in the Caddo-Kiowa Technology Center STEM Day together with 150 high school students. Thanks to the Gallogly College of Engineering outreach team, the Stephenson School of Biomedical Engineering, and Prof. Rebecca Scott for the support.
NSF GRFP Award
March 2023 – Wilhelm Lab undergraduate student Rylee Newport received the NSF GRFP award! Outstanding accomplishment, Rylee!
Publication in Nature Materials
March 2023 – Lin Wang published a News & Views article in the journal Nature Materials.
L. Wang, S. Wilhelm, “Exploiting endothelial transcytosis to reach into the brain”
Nature Materials, 2023, 22, 282-283
DOI: 10.1038/s41563-023-01487-3 | PDF (2.8 MB)
Gallogly College of Engineering Teaching Award
February 2023 – Stefan received the Gallogly College of Engineering Teaching Scholar Award. Thank you to all students and colleagues for your support!
Publication in Analytical and Bioanalytical Chemistry
January 2023 – Alex Frickenstein, Shirsha Mukherjee, and the team published a research article in the journal Analytical and Bioanalytical Chemistry.
A. N. Frickenstein, S. Mukherjee, T. Harcourt, Y. He, V. Sheth, L. Wang, Z. Malik, S. Wilhelm, “Quantification of monodisperse and biocompatible gold nanoparticles by single-particle ICP-MS”
Analytical and Bioanalytical Chemistry, 2023, accepted.
DOI: 10.1007/s00216-023-04540-x | PDF (5.3 MB)
Publication in Micro
January 2023 – Nathan, Ellen, Vinit, and Emmy published a research article in Micro.
SYNTHESIS, CHARACTERIZATION, AND ACUTE CYTOTOXICITY EVALUATION OF CHLOROQUINE ENCAPSULATING LIPOSOMES
N. D. Donahue, E. Vance, V. Sheth, E. Francek, S. Wilhelm, “Synthesis, characterization, and acute cytotoxicity evaluation of chloroquine encapsulating liposomes”
Micro, 2023, 3, 1, 51-59.
DOI: 10.3390/micro3010005 | PDF (1.3 MB)
BE4NANO Classroom Visits 2022
November 2022 – Our SBME faculty team visited the pre-engineering and biomedical sciences high school classrooms at the Caddo-Kiowa Technology Center in Fort Cobb to engage students in bionanotechnology, bioimaging, and biomedical engineering.
Tekena Harcourt Received Pursuit of Excellence Award
October 2022 – Tekena, a current BME junior in the Wilhelm Lab, received the Gallogly College of Engineering Pursuit of Excellence Award. Congratulations Tekena!
Publication in Advanced Science
September 2022 – Vinit is a co-author of a collaborative research project led by Prof. Mukherjee (OUHSC). The paper has been published in Advanced Science.
GOLD NANOPARTICLES DISRUPT THE IGFBP2/MTOR/PTEN AXIS TO INHIBIT OVARIAN CANCER GROWTH
M.N. Hossen, L.Wang, S.K.D. Dwivedi, Y. Zhang, G. Rao, C.K. Elechalwar, V. Sheth, A. Dey, S. Asfa, S.K. Gulla, C. Xu, K. Fung, J.D. Robertson, M. Bieniasz, S. Wilhelm, R. Bhattacharya, P. Mukherjee, “Gold nanoparticles disrupt the IGFBP2/mTOR/PTEN axis to inhibit ovarian cancer growth”
Advanced Science, 2022, published.
DOI: 10.1002/advs.202200491 | PDF (11.1 MB)
Publication in Advanced Photonics Research
September 2022 – Evan Mettenbrink and Wen Yang published a review paper in Advanced Photonics Research.
BIOIMAGING WITH UPCONVERSION NANOPARTICLES
E. Mettenbrink, W. Yang, S. Wilhelm, “Bioimaging with upconversion nanoparticles”
Advanced Photonics Research, 2022, published.
DOI: 10.1002/adpr.202200098 | PDF (2.2 MB)
Publication in Nano Letters
September 2022 – Wen Yang and her team published a paper in Nano Letters in collaboration with colleagues from OUHSC.
CONTROLLING NANOPARTICLE UPTAKE IN INNATE IMMUNE CELLS WITH HEPAROSAN POLYSACCHARIDES
W. Yang, A. N. Frickenstein, A. M. Holden, V. Sheth, E. M. Mettenbrink, L. Wang, A. Woodward, B. Joo, S. Butterfield, N. D. Donahue, D. E. Green, A. Thomas, T. Harcourt, Y. Hamilton, M. Tang, Z. Malik, R. Harrison, P. Mukherjee, P. L. DeAngelis, S. Wilhelm, “Controlling nanoparticle uptake in innate immune cells with heparosan polysaccharides.”
Nano Letters, 2022, published.
DOI: 10.1021/acs.nanolett.2c02226 | PDF (6.5 MB)
OVPRP Faculty Fellow
August 2022 – Stefan Wilhelm has been named the Faculty Fellow of the University of Oklahoma Vice President for Research and Partnership (OVPRP) office.
Presbyterian Health Foundation Team Grant
July 2022 – Wilhelm Lab received funding support for a Team Grant from the Presbyterian Health Foundation.
Ph.D. Defense – Wen Yang
July 2022 – Wen Yang defended her Ph.D. thesis with the title “A novel polysaccharide-based surface engineering strategy for nanomedicines”. Congratulations, Dr. Yang! Thank you to the Ph.D. committee members, Drs. Handan Acar, Qinggong Tang, and Zhibo Yang.
Wilhelm Lab Team 2022
July 2022 – The Wilhelm Lab team members in Summer 2022. An amazing group of young scientists and engineers.
PC: Travis Caperton.
