The Biomedical Nano-Engineering (BNE) Laboratory led by Dr. Stefan Wilhelm has broad interest in engineering colloidal nanomaterials for diagnosis and treatment of diseases, including cancer. Our areas of expertise include the design and synthesis of organic and inorganic nanomaterials with defined physicochemical properties (e.g., size, shape, surface chemistry, optical/magnetic features).

Our group aims to study and understand interactions between nanomaterials and biological systems from a whole organ/tissue perspective down to the cellular and bio-molecular level. This research will provide a foundation for the rational engineering of nanomaterials and nanomedicines with the ultimate goal to design diagnostic and therapeutic strategies for clinical translation.
 

Research Interests

Engineering nanotechnology for diagnosis, detection and treatment of diseases.

Biosensors
Cancer nanomedicine
Immunoengineering and immunomodulation
Nanotechnology-biology (“nano-bio”) interactions
Three-dimensional optical imaging
 

Instrumentation and Equipment

Agilent Cary 5000 UV-Vis-NIR Spectrophotometer
Azur C600 UV-Vis-NIR Imaging System
BioTek Synergy Neo2 Multi-Mode Plate Reader
Branson 3800 Ultrasonic Cleaner
Büchi Rotavap R-100
Chemglass Schlenk Line
DeNovix CellDrop BF Cell Counter and D11+ Spectrophotometer
Eppendorf 5427R and 5910R Centrifuges
Eppendorf Galaxy 170 S  and CellXpert Cell Incubators
Freezers (-20°C) and Fridges (4°C)
Harrick Basic Plasma Cleaner
Horiba PTI Quanta Master 8000 Fluorometer
Hoshizaki Ice Maker
Keyence BZ-X800 Automated Fluorescence Microscope
Labconco Logic Plus Biological Safety Cabinet and FreeZone Freeze Dryer
Malven ZetaSizer Nano ZS
Mettler Toledo S220 pH Meter
MVE Cryosystem 6000 Cell Storage
Nova Automated Water Bath
Olympus CKX53 Optical Microscope
PHCBI Minus 80°C Freezer
Purist Pro UV Ultrapure Water System
Sartorius Analytical and Precision Balances
Steris AMSCO 250 LS Autoclaves
Thermo Heraeus Multifuge X3R and Fresco 21 Centrifuges

 

Funding Sources

Our research is supported by the following agencies: