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WILHELM LAB

Biomedical Nano-Engineering Laboratory

OU stephenson-biomedical-engineeringThe Wilhelm Lab is affiliated with the Stephenson School of Biomedical Engineering (SBME) at the University of Oklahoma (OU).

Our lab space is in Gallogly Hall at the OU Norman Campus.

Our research interests include engineering and design of nanomaterials for use in biomedical applications and clinical translation.


WILHELM LAB NEWS

Outstanding Sophomore Award to Emmy Francek

July 2020 – Emmy Francek received the SBME Oustanding Sophomore Award 2020.

Publication in Science Advances

July 2020 – Stefan Wilhelm co-authored a research article in the journal Science Advances.

N. Hossen, L. Wang, H. R. Chinthalapally, J. D. Robertson, K. M. Fung, S. Wilhelm, M. Bieniasz, R. Bhattacharya, P. Mukherjee, “Switching intracellular pathway and enhancing therapeutic efficacy of small interfering RNA by auroliposome.”
Science Advances, 2020, 6, 30, eaba5379.

DOI: 10.1126/sciadv.aba5379PDF (2.3 MB)

Publication in Analytical and Bioanalytical Chemistry

July 2020 – Nathan Donahue, Emmy Francek, Emi Kiyotake, Emily Thomas, Wen Yang, and Lin Wang published a research article in the journal Analytical and Bioanalytical Chemistry.

N. D. Donahue, E. R. Francek, E. Kiyotake, E. E. Thomas, W. Yang, L. Wang, M. S. Detamore, S. Wilhelm, “Assessing nanoparticle colloidal stability with Single-Particle Inductively Coupled Plasma Mass Spectrometry (SP-ICP-MS).”
Analytical and Bioanalytical Chemistry, 2020, accepted.

DOI: 10.1007/s00216-020-02783-6PDF (2.1 MB)

Nature Materials Cover – May 2020 Issue

May 2020 – “The entry of nanoparticles into solid tumours” by Sindhwani et al. is highlighted on the May 2020 journal cover of Nature Materials.

S. Sindhwani, A.M. Syed, J. Ngai, B.R. Kingston, L. Maiorino, J. Rothschild, P. MacMillan, Y. Zhang, N.U. Rajesh, T. Hoang, J.L.Y. Wu, S. Wilhelm, A. Zilman, S. Gadde, A. Sulaiman, B. Ouyang, Z. Lin, L. Wang, M. Egeblad, W.C.W. Chan, “The entry of nanoparticles into solid tumours”
Nature Materials, 2020, 19, 566-575.

DOI: 10.1038/s41563-019-0566-2PDF (7.2 MB)

2020 – Nature Materials

Dr. Lin Wang joined Wilhelm Lab as Postdoctoral Research Fellow

March 2020 – Dr. Lin Wang joined Wilhelm Lab as Postdoctoral Research Fellow.

Presentation Award to Nathan Donahue

March 2020 – Congratulations to our Ph.D. student Nathan Donahue on winning a presentation award at the Oklahoma Microscopy Society Annual Meeting for his talk “Characterizing and Fine-tuning Nanomaterials for Biomedical Applications”.

BE4NANO DAY 2020

March 2020 – High School Junior students from the Caddo-Kiowa Technology Center in Fort Cobb visited our lab as part of the 1st BE4NANO DAY to learn more about our bionanotechnology research, college admission, and the University of Oklahoma.

BE4NANO – Visit of Paoli High School

February 2020 – We visited Paoli High School as part of our “Bionanotechnology Engagement for Native Americans in Oklahoma” BE4NANO outreach and education initiative. Thank you for the invitation!

Publication in ACS Applied Nano Materials

February 2020 – Joanne Lee, Nathan Donahue, Angelina Mao, Amber Karim, Emily Thomas, Emmy Francek, and Wen Yang published a research article in the journal ACS Applied Nano Materials.

C. Lee*, N. D. Donahue*, A. S. Mao, A. Karim, M. Komarneni, E. E. Thomas, E. R. Francek, W. Yang, S. Wilhelm, “Exploring maleimide-based nanoparticle surface engineering to control cellular interactions”
ACS Applied Nano Materials, 2020, 3, 3, 2421-2429

DOI: 10.1021/acsanm.9b02541 | PDF (3.2 MB)

Publication in Nature Materials

January 2020 – Stefan Wilhelm co-authored a research article in the journal Nature Materials.

S. Sindhwani, A.M. Syed, J. Ngai, B.R. Kingston, L. Maiorino, J. Rothschild, P. MacMillan, Y. Zhang, N.U. Rajesh, T. Hoang, J.L.Y. Wu, S. Wilhelm, A. Zilman, S. Gadde, A. Sulaiman, B. Ouyang, Z. Lin, L. Wang, M. Egeblad, W.C.W. Chan, “The entry of nanoparticles into solid tumours”
Nature Materials, 2020, 19, 566-575.

DOI: 10.1038/s41563-019-0566-2PDF (7.2 MB)

Publication in Nano Letters

January 2020 – Stefan Wilhelm co-authored a research article in the journal Nano Letters.

A.M. Syed, P. MacMillan, J. Ngai, S. Wilhelm, S. Sindhwani, B.R. Kingston, J.L.Y. Wu, P. Llano-Suárez, Z. . Lin, B. Ouyang, Z. Kahiel, S. Gadde, W.C.W. Chan, “Liposome imaging in optically cleared tissues”
Nano Letters, 2020, 2, 1362-1369.

DOI: 10.1021/acs.nanolett.9b04853PDF (7.6 MB)

IBEST-OUHSC Seed Grant 2019

December 2019 – Wilhelm Lab received the IBEST-OUHSC Interdisciplinary Research Seed Grant 2019.

Invited Talk at AIChE 2019 in Orlando

November 2019 – Stefan Wilhelm delivered an invited keynote talk at the 2019 AIChE Annual Meeting in Orlando, FL.

BE4NANO – Visit of Riverside Indian School in Anadarko

November 2019 – As part of the “Bionanotechnology Engagement for Native Americans in Oklahoma” (BE4NANO) outreach and education initiative, Wilhelm Lab visited Riverside Indian School in Anadarko to engage students in classroom hands-on demonstrations.

Publication of Book Chapter

November 2019 – Steven Narum, Tram Le, Joanne Lee, Grace Le, Nathan Donahue, and Wen Yang published book chapter.

M. Narum, T. Le, D.P. Le, J.C. Lee, N.D Donahue, W. Yang, S. Wilhelm, “Passive targeting in nanomedicine: fundamental concepts, body interactions, and clinical potential
In Nanoparticles for Biomedical Applications, Elsevier, 2020, 37-53

DOI: 10.1016/B978-0-12-816662-8.00004-7 | PDF (3 MB)