Contact: weny@ou.edu 
LAB POSITION
Ph.D. Graduate Student, July 2019 – July 2022
BIOGRAPHY
Undergraduate Institution
- Medical College, Major: M.B.B.S.: Bachelor of medicine, bachelor of surgery; an international medical degree equivalent to an M.D. in the U.S. system
- China Three Gorges University, Yichang City, China
AWARDS & HONORS
- 2022: Gallogly College of Engineering Dissertation Excellence Award
- 2021: Robberson Travel Grant
- 2021: IBEST student travel award
- 2021: Poster presentation in Biomedical Engineering Society, Orlando
- 2021: Poster presentation in END2Cancer, Virtual
PUBLICATIONS
Wilhelm Lab Publications
2022
CONTROLLING NANOPARTICLE UPTAKE IN INNATE IMMUNE CELLS WITH HEPAROSAN POLYSACCHARIDES
W. Yang, A. N. Frickenstein, A. M. Holden, V. Sheth, E. M. Mettenbrink, L. Wang, A. Woodward, B. Joo, S. Butterfield, N. D. Donahue, D. E. Green, A. Thomas, T. Harcourt, Y. Hamilton, M. Tang, Z. Malik, R. Harrison, P. Mukherjee, P. L. DeAngelis, S. Wilhelm, “Controlling nanoparticle uptake in innate immune cells with heparosan polysaccharides”
Nano Letters, 2022, published.
DOI: 10.1021/acs.nanolett.2c02226 | PDF (6.5 MB)
DISABLING PARTNERS IN CRIME: GOLD NANOPARTICLES DISRUPT MULTICELLULAR COMMUNICATIONS WITHIN THE TUMOR MICROENVIRONMENT TO INHIBIT OVARIAN TUMOR AGGRESSIVENESS
Y. Zhang, C.K. Elechalawar, W. Yang, A. Frickenstein, S. Asfa, K.M. Fung, B. N. Murphy, S. K. Dwivedi, G. Rao, A. Dey, S. Wilhelm, R. Bhattacharya, P. Mukherjee, “Disabling partners in crime: Gold nanoparticles disrupt multicellular communications within the tumor microenvironment to inhibit ovarian tumor aggressiveness.”
Materials Today, 2022, published online.
DOI: 10.1016/j.mattod.2022.01.025 | PDF (9.9 MB)
NANOPARTICLE SURFACE ENGINEERING WITH HEPAROSAN POLYSACCHARIDE REDUCES SERUM PROTEIN ADSORPTION AND ENHANCES CELLULAR UPTAKE
W. Yang, L. Wang, M. Fang, V. Sheth, Y. Zhang, A. M. Holden, N. D. Donahue, D. E. Green, A. N. Frickenstein, E. M. Mettenbrink, T. A. Schwemley, E. R. Francek, M. Haddad, Md N. Hossen, S. Mukherjee, S. Wu, P. L. DeAngelis, S. Wilhelm, “Nanoparticle surface engineering with heparosan polysaccharide reduces serum protein adsorption and enhances cellular uptake”
Nano Letters, 2022, published online.
DOI: 10.1021/acs.nanolett.2c00349 | PDF (5.6 MB)
2021
NANOPARTICLE TOXICOLOGY
W. Yang, L. Wang, E. Mettenbrink, P. L. DeAngelis, S. Wilhelm, “Nanoparticle toxicology“
Annual Review of Pharmacology and Toxicology, 2021, 61, 269-289.
DOI: 10.1146/annurev-pharmtox-032320-110338 | PDF (1.9 MB)
2020
ASSESSING NANOPARTICLE COLLOIDAL STABILITY WITH SINGLE-PARTICLE INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY (SP-ICP-MS)
N. D. Donahue, E. R. Francek, E. Kiyotake, E. E. Thomas, W. Yang, L. Wang, M. S. Detamore, S. Wilhelm, “Assessing nanoparticle colloidal stability with Single-Particle Inductively Coupled Plasma Mass Spectrometry (SP-ICP-MS)”
Analytical and Bioanalytical Chemistry, 2020, 412, 5205-5216.
DOI: 10.1007/s00216-020-02783-6 | PDF (2.1 MB)
Highlighted on journal cover page (Analytical and Bioanalytical Chemistry; Volume: 412; Issue: 22; September 2020)
EXPLORING MALEIMIDE-BASED NANOPARTICLE SURFACE ENGINEERING TO CONTROL CELLULAR INTERACTIONS
C. Lee*, N.D. Donahue*, A.S. Mao, A. Karim, M. Komarneni, E.E. Thomas, E.R. Francek, W. Yang, S. Wilhelm, “Exploring maleimide-based nanoparticle surface engineering to control cellular interactions”
ACS Applied Nano Materials, 2020, accepted.
DOI: 10.1021/acsanm.9b02541 | PDF (3.2 MB)
PASSIVE TARGETING IN NANOMEDICINE: FUNDAMENTAL CONCEPTS, BODY INTERACTIONS, AND CLINICAL POTENTIAL
S.M. Narum, T. Le, D.P. Le, J.C. Lee, N.D Donahue, W. Yang, S. Wilhelm, “Passive targeting in nanomedicine: fundamental concepts, body interactions, and clinical potential”
In Nanoparticles for Biomedical Applications, Elsevier, 2020, 37-53